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Category Archives: cocaine

Methadone and Perinatal Outcomes – a Prospective Cohort Study

Friday, February 17, 2012

Abstract Aims: Aims–Methadone use in pregnancy has been associated with adverse perinatal outcomes and neonatal abstinence syndrome (NAS). This study aimed to examine perinatal outcomes and NAS in relation to i)concomitant drug use and ii)methadone dose. Design: Design–Prospective cohort study.

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Influence of acute bupropion pre-treatment on the effects of intranasal cocaine

Saturday, February 11, 2012

ABSTRACT Aims  The aim of this experiment was to determine the influence of acute bupropion pre-treatment on subject-rated effects and choice of intranasal cocaine versus money. Design  A randomized, within-subject, placebo-controlled, double-blind experiment. Setting  An out-patient research unit

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Assessment of Exposure to Drugs of Abuse During Pregnancy by Hair Analysis in a Mediterranean Island

Wednesday, February 1, 2012

Abstract Aims: The study aims to estimate the prevalence of drug use by pregnant women living in Ibiza, using structured interviews and biomarkers in maternal hair In addition, the potential detrimental effects of maternal drug abuse on their newborns were investigated. Ibiza has a large international night-life resort associated with clubs, music and use of recreational drugs

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Addicts’ Cravings Have Different Roots In Men And Women

Wednesday, February 1, 2012

When it comes to addiction, sex matters. A new brain imaging study by Yale School of Medicine researchers suggests stress robustly activates areas of the brain associated with craving in cocaine-dependent women, while drug cues activate similar brain regions in cocaine-dependent men. The study, expected to be published online Jan…

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A longitudinal study of substance use and violent victimization in adulthood among a cohort of urban African Americans

Wednesday, February 1, 2012

ABSTRACT Aims  This paper examines the effects of experiencing violent victimization in young adulthood on pathways of substance use from adolescence to mid-adulthood. Design  Data come from four assessments of an African American community cohort followed longitudinally from age 6 to 42 years. Setting  The cohort lived in the urban, disadvantaged Woodlawn neighborhood of Chicago in 1966

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Sex work involvement among women with long-term opioid injection drug dependence who enter opioid agonist treatment

Wednesday, January 25, 2012

Background: Substitution with opioid-agonists (e.g., methadone) has shown to be an effective treatment for chronic long-term opioid dependency.

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Implementation and Evaluation of a Harm-Reduction Model for Clinical Care of Substance Using Pregnant Women

Thursday, January 19, 2012

Background: Methamphetamine (MA) use during pregnancy is associated with many pregnancy complications, including preterm birth, small for gestational age, preeclampsia, and abruption. Hawaii has lead the nation in MA use for many years, yet prior to 2007, did not have a comprehensive plan to care for pregnant substance-using women. In 2006, the Hawaii State Legislature funded a pilot perinatal addiction clinic

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The rising prevalence of prescription opioid injection and its association with hepatitis C incidence among street-drug users.

Monday, January 16, 2012

Abstract Aims: To examine trends in prescription opioid (PO) injection and to assess its association with hepatitis C virus (HCV) seroconversion among injection drug users (IDUs).

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The rising prevalence of prescription opioid injection and its association with hepatitis C incidence among street-drug users.

Monday, January 16, 2012

Abstract Aims: To examine trends in prescription opioid (PO) injection and to assess its association with hepatitis C virus (HCV) seroconversion among injection drug users (IDUs). Design: Prospective cohort study. Setting: Montreal, Canada.

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How The Brain Puts The Brakes On The Negative Impact Of Cocaine

Friday, January 13, 2012

Research published by Cell Press in the journal Neuron provides fascinating insight into a newly discovered brain mechanism that limits the rewarding impact of cocaine. The study describes protective delayed mechanism that turns off the genes that support the development of addiction-related behaviors…

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