Abstract Aims: Given rising rates of the nonmedical use of prescription medications (NUPM) and strong cross-sectional associations between psychopathology and NUPM, we examined whether a history of NUPM increased the risk for onset and recurrence of psychopathology. Design: Longitudinal data are from waves 1 and 2 of the National Epidemiological Survey on Alcoholism and Related Conditions (NESARC). Setting: The NESARC is a nationwide, household-based survey.
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