Abstract Aims. Sublingual buprenorphine and buprenorphine/naloxone are efficacious opioid dependence pharmacotherapies, but there are reports of their diversion and misuse by the intranasal route. The study objectives were to characterize and compare their intranasal pharmacodynamic and pharmacokinetic profiles
Filed in Evidence Base
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Also tagged abuse-potential, all-intranasal, diversion, from-intranasal, intranasal, reported-higher, subjective, the-intranasal, the-likelihood, their-diversion, university
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Friday, December 17, 2010
New research indicates that ingesting moderate amounts of alcohol may increase an individual’s risk of amphetamine abuse Amphetamines are part of a large group of drugs known as stimulants, which are commonly misused in the United States A new study shows that the amount of alcohol consumed may increase the likelihood of developing drug abuse These results indicate th…
Wednesday, December 1, 2010
Background: There is good evidence for the effectiveness of opioid substitution therapy (OST) for injecting drug users (IDUs) in middle and high-income countries but little evidence regarding the provision of OST by non-government organisations (NGOs) in resource-poor settings. This paper reports on outcomes of an NGO-based OST program providing sub-lingual buprenorphine to opiate dependent IDUs in two north-east Indian states (Manipur and Nagaland), a region where conflict, under-development and injecting of heroin and Spasmoproxyvon (SP) are ongoing problems. The objectives of the study were: 1) to calculate OST treatment retention, 2) to assess the impact on HIV risk behaviours and quality of life, and 2) to identify client characteristics associated with cessation of treatment due to relapse.
Filed in Harm Reduction
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Also tagged best-classified, binary-logistic, effectiveness, indian, little-evidence, manipur, operational, ost, provision, risk-behaviours, spasmoproxyvon
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Certain personality traits, demographic and work related factors increase the likelihood that doctors will develop mental illness or hazardous alcohol habits according to a study published in the Medical Journal of Australia…
Objective We hypothesized that the drinking behavior of adolescents in China is influenced by expectancies and self-efficacy and that adolescents’ cultural orientation towards western versus traditional Chinese values influences expectancies, self-efficacy and drinking behavior, with western values leading to more dysfunctional patterns of beliefs and drinking, and that these beliefs are influenced by students’ gender and school environment.Methods A total of 1020 high school students from Beijing completed the Chinese Adolescent Alcohol Expectancy, the Chinese Cultural Orientation and the Chinese Self-regulation Self-efficacy questionnaires.Results Results generally confirmed our hypotheses. Higher negative expectancies and higher self-efficacy reduced the likelihood of drinking significantly. Higher positive expectancies increased the likelihood of regular drinking but not occasional drinking
Conclusions: While these data do not allow us to make causal interpretations, our results suggest an association between SLE and ND. Potentially, individuals experiencing SLEs may find it difficult to quit smoking; alternatively, directly or via correlated risks (e.g., living in a high risk neighborhood), smoking may increase the likelihood of exposure to SLEs. PMID: 19199167 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse)
Filed in Evidence Base
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Also tagged alcohol, directly-or-via, increase-the-likelihood, make-causal, our-results, pmid, quit-smoking, results, smoking-may, these-data, via-correlated
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